[MassSpecGroup] MassSpecGroup Digest, Vol 23, Issue 7

[Rekha]

Hi Chang,

I couldn't able to come to last group meeting, as we have some tight
deadlines for FDA submissions going on at work. Good luck for your
defence...I know you'll do good...

Rekha



On Thu, Oct 28, 2010 at 12:00 PM,
<massspecgroup-request at lists.stevens.edu>wrote:

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> Today's Topics:
>
>   1. Reminder: Chang-Ching's Defense is Today (Freneil Jariwala)
>   2. Chang-Ching's Abstract (Freneil Jariwala)
>
>
> ----------------------------------------------------------------------
>
> Message: 1
> Date: Thu, 28 Oct 2010 08:54:49 -0400
> From: Freneil Jariwala <fjariwal at stevens.edu>
> Subject: [MassSpecGroup] Reminder: Chang-Ching's Defense is Today
> To: MassSpecGroup <massspecgroup at lists.stevens.edu>
> Message-ID:
>        <AANLkTimZh8RRY2YU+XT8Vjv8pkzF7DLOGEYASdaZRE3i at mail.gmail.com<AANLkTimZh8RRY2YU%2BXT8Vjv8pkzF7DLOGEYASdaZRE3i at mail.gmail.com>
> >
> Content-Type: text/plain; charset="iso-8859-1"
>
> Hello Everyone,
>
> Just a reminder that today is Chang-Ching's Ph.D. Defense. It will take
> place at 2:00 pm in McLean 510 Conference Room. Please arrive early if you
> plan to attend as seating might be limited.
>
> Good Luck Chang-Ching...Break a Leg!!!
>
> --
> Freneil Jariwala
> Graduate Student
> Department of Chemistry, Chemical Biology, and Biomedical Engineering
> Stevens Institute of Technology
> Hoboken, NJ 07030
> fjariwal at stevens.edu
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> Message: 2
> Date: Thu, 28 Oct 2010 08:56:05 -0400
> From: Freneil Jariwala <fjariwal at stevens.edu>
> Subject: [MassSpecGroup] Chang-Ching's Abstract
> To: MassSpecGroup <massspecgroup at lists.stevens.edu>
> Message-ID:
>        <AANLkTimy+uxP3DRU5MStZo9D1zUPDSDAjpo9Cwdk=+6h at mail.gmail.com>
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>
> Here is Chang-Ching's Abstract:
>
> A new desorption ionization technique, Desorption Ionization by Charge
> Exchange
> (DICE), has been developed and used to analyze compounds that do not ionize
> well
> by existing Electrospray-related desorption techniques, e.g. Desorption
> Electrospray
> Ionization (DESI). In the DICE technique, a nebulized spray containing
> molecular ions
> of a solvent such as toluene is generated by passing the solvent through a
> stainless steel
> capillary held at a high voltage. When the stream of charged droplets
> produced in this
> way is directed onto a solid surface, the analytes present on the surface
> are desorbed and
> ionized by a charge exchange process. This technique was shown to desorb
> and
> generate
> molecular ions from compounds that are not readily ionized by some other
> ambient
> methods, under positive-ion generation mode. In addition, DICE has shown to
> generate
> minimal metal cation adducts which some scientists would consider to be
> spectral
> complications. Another important feature about DICE is that it can be
> easily
> combined
> with DESI to broaden the range of compounds that can be analyzed by mass
> spectrometry
> within a single experiment since DICE works better for some compounds while
> DESI
> works better for other compounds. The combined technique could generate the
> molecular
> ion, proton and metal adduct from the same compound. When coupled to a
> tandem mass
> spectrometer, the combined source enables the generation of product ion
> spectra of the
> molecular ion and those of the [M + H]+ or [M + metal]+ ions of the same
> compound,
> without having to physically change the source from DICE to DESI. The
> ability to record
> CID spectra of both the molecular ion and adduct ions in a single mass
> spectrometric
> experiment adds a new dimension to the array of mass spectral methods
> available for
> structural studies.
>
> --
> Freneil Jariwala
> Graduate Student
> Department of Chemistry, Chemical Biology, and Biomedical Engineering
> Stevens Institute of Technology
> Hoboken, NJ 07030
> fjariwal at stevens.edu
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